Scientific Posters

Download our latest scientific posters

Research our scientists have presented at leading toxicology conferences. Free to view and download.

A Weight of Evidence Review on the Mode of Action, Adversity, and the Human Relevance of Xylene’s Observed Thyroid Effects in Rats
EUROTOX 2025

A Weight of Evidence Review on the Mode of Action, Adversity, and the Human Relevance of Xylene’s Observed Thyroid Effects in Rats

A weight of evidence review showing that xylene’s thyroid effects in rats come from liver enzyme induction, are not relevant to humans, and do not support classifying xylene as an endocrine disruptor.

In vitro metabolism of ethylbenzene and xylene isomers in rat liver S9
EUROTOX 2025

In vitro metabolism of ethylbenzene and xylene isomers in rat liver S9

An in vitro study showing that ethylbenzene and the three xylene isomers are metabolised at the same rate, alone or as a mixture, supporting read-across between xylene substances under REACH.

Xylene: weight of evidence approach case study to determine the need for an extended one generation reproductive study with a developmental neurotoxicity animal cohort
EUROTOX 2025

Xylene: weight of evidence approach case study to determine the need for an extended one generation reproductive study with a developmental neurotoxicity animal cohort

A weight of evidence review concluding that xylene’s narcotic effects are transient and reversible, and that there is no trigger for an additional developmental neurotoxicity cohort in an EOGRT study.