Our peer-reviewed publications reflect Penman Consulting’s contribution to regulatory science and policy development, supporting evidence-based decision making across chemical and product regulation.
Scientific Publications
Peer-reviewed research and regulatory science underpinning our advisory work
2025
Prenatal developmental toxicity evaluation of higher olefins in Sprague-Dawley rats. Reproductive Toxicology, Volume 132.
Quan S, Michael G. Penman, Juan-Carlos Carrillo, Jamie Dunn, Hua Shen, Sophie Jia, An R. Van Rompay, Fabienne Hubert, Peter J. Boogaard, 2025.
2025
Xylene: weight of evidence approach case study to determine the need for an extended one generation reproductive study with a developmental neurotoxicity animal cohort. Critical Reviews in Toxicology, 54(10), 925–952.
Frank Faulhammer, Martijn Rooseboom, Neslihan Aygun Kocabas, Josje H. E. Arts, Alexandra Cordova, Elaine Freeman, Larry G. Higgins, Muna Nahar, Emily Richmond, Steffen Schneider & Keith Morris-Schaffer, 2025.
2024
Utility of in vivo metabolomics to support read-across for UVCB substances under REACH. Archives of Toxicology.
H. Kamp, N. Aygun Kocabas, F. Faulhammer, N. Synhaeve, E. Rushton, B. Flick, V. Giri, S. Sperber, L. G. Higgins, M. G. Penman, B. van Ravenzwaay & M. Rooseboom, 2024.
2023
Toxicological Assessment of Higher Olefins in OECD TG 422 Repeated Dose and Reproductive/Developmental Toxicity Screening Tests in Han Wistar Rats. International Journal of Toxicology.
Quan Shi, Juan-Carlos Carrillo, Michael G Penman, Hua Shen, Colin M North, Sophie Jia, Tilly Borsboom-Patel, Yuan Tian, Fabienne Hubert, Jason C Manton, Peter J Boogaard, 2023.
2020
Evaluation of repeated dose and reproductive / developmental toxicity of 1,2-Cyclohexanedicarboxylic Acid, 1-butyl 2 (phenylmethyl) ester (P1400) in the rat. The Toxicologist, Supplement to Toxicological Sciences, 168 (1), Abstract #1540.
Segal, L., Garcia, S., Canut, L.,Diaram, S., David, R., Xu, J., and Penman, M., 2019.
2017
Extended OECD 422 screening study for the evaluation of substances with suspected reproductive toxicity and/or endocrine activity. Toxicology Letters, 280, p.S163.
Segal, L., Canut, L., Myers, D., García, S., Blee, M., Butala, J. and Penman, M., 2017.
2016
Strategies to address REACH Annex X requirements for developmental toxicity testing in a second mammalian species. Society of Toxicology Annual Meeting 2016, Late‐Breaking Abstracts Poster abstract ID: 3614 Poster Board: P306
Penman, M., Riley, A.,Candido, A.,Wood, E., Myers, D. and Segal, L. 2016.