Scientific Publications

Peer-reviewed research and regulatory science underpinning our advisory work

Our peer-reviewed publications reflect Penman Consulting’s contribution to regulatory science and policy development, supporting evidence-based decision making across chemical and product regulation.

Filter by Tags

All Publications 33

Alternative methods 5 Data Assessment 1 Dermal 1 Endocrine 2 Environmental 1 Epidemiology 2 Exposure Assessment 1 Genotoxicology 1 Mechanistic 10 Metabolism 1 REACH 10 Reproduction 11 Risk Management 1 Testing Strategies 7 Toxicology 24

Currently filtering by:

Endocrine

2025

A weight of evidence review on the mode of action, adversity, and the human relevance of xylene’s observed thyroid effects in rats. Critical Reviews in Toxicology, 1–26.

Keith Morris-Schaffer, Larry Higgins, Neslihan Aygun Kocabas, Frank Faulhammer, Alexandra Cordova, Elaine Freeman, Hennicke Kamp, Muna Nahar, Emily Richmond, Martijn Rooseboom, 2025.

2025

Xylene: weight of evidence approach case study to determine the need for an extended one generation reproductive study with a developmental neurotoxicity animal cohort. Critical Reviews in Toxicology, 54(10), 925–952.

Frank Faulhammer, Martijn Rooseboom, Neslihan Aygun Kocabas, Josje H. E. Arts, Alexandra Cordova, Elaine Freeman, Larry G. Higgins, Muna Nahar, Emily Richmond, Steffen Schneider & Keith Morris-Schaffer, 2025.